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Table 1 Total binding energies of the 19 epitope candidates (in descending HLA-B*4405 binding energy ranks).

From: Molecular docking analysis of 2009-H1N1 and 2004-H5N1 influenza virus HLA-B*4405-restricted HA epitope candidates: implications for TCR cross-recognition and vaccine development

Position Sequence Docked to HLA-B*4405 Docked to DM1-TCR
Energy Rank Energy Rank
240 QEGRMNYYW -1,006 1 -541.7 17
188 KEVLVLWGI -921.8 2 -573.9 13
128 FERFEIFPK -869.9 3 -594.6 12
482 FEFYHKCDN -846.8 4 -743.9 2
259 FEATGNLVV -815.2 5 -608.9 10
400 IEKMNTQFT -775.8 6 -688.5 5
131 FEIFPKTSS -752.9 7 -560.5 14
251 VEPGDKITF -743.3 8 -599.1 11
229 PEIAIRPKV -687.7 9 -548.9 15
50 LEDKHNGKL -661.4 10 -552.1 16
274 MERNAGSGI -644 11 - -
514 REEIDGVKL -643.8 12 -666.3 7
81 PECESLSTA -633.3 13 - -
446 LENERTLDY -603.1 14 -621.1 9
412 KEFNHLEKR -599.5 15 -737.2 3
493 MESVKNGTY -543 16 -645 8
475 KEIGNGCFE -519.6 17 -715.4 4
463 YEKVRSQLK -475.3 18 -751.3 1
421 IENLNKKVD -464.6 19 -666.7 6