Table 3 Seven 2009-H1N1 T cell epitope candidates that could be cross-reactive with 2004-H5N1 T cell responses.
2009_H1N1 position | Strain | Sequence | MHC-bound predicted score | Docked to HLA-B*4405 | Docked to DM1-TCR |
|---|---|---|---|---|---|
Energy | Energy | ||||
50 | 2009-H1N1 | LED K HNGKL | 1.0508 | -661.4 | -552.1 |
| Â | 2004-H5N1 | LEKT HNGKL | 1.1478 | -715.0 | -682.2 |
412 | 2009-H1N1 | K EFNH LEKR | 0.9764 | -599.5 | -737.2 |
| Â | 2004-H5N1 | R EFNN LEKR | 0.9949 | -638.9 | -640.8 |
446 | 2009-H1N1 | L ENE RTLD Y | 1.1929 | -603.1 | -621.1 |
| Â | 2004-H5N1 | M E NER TLDF | 1.5813 | -563.5 | -667.2 |
493 | 2009-H1N1 | M ESVK NGTY | 1.73 | -543.0 | -645.0 |
| Â | 2004-H5N1 | MES VR N GTY | 1.6645 | -595.0 | -667.5 |
421 | 2009-H1N1 | IENLNKK V D | 0.8563 | -464.6 | -666.0 |
| Â | 2004-H5N1 | IENLNKKME | 0.7968 | -466.1 | -642.0 |
475 | 2009-H1N1 | KE I GNGCFE | 0.9892 | -519.6 | -715.4 |
| Â | 2004-H5N1 | K EL GNGCFE | 0.8258 | -548.9 | -733.8 |
482 | 2009-H1N1 | FEFYHK CDN | 1.1128 | -846.8 | -743.9 |
| Â | 2004-H5N1 | FEFYHK CDN | 1.1129 | -846.8 | -743.9 |