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Table 4 Mouse and human virus target similar KEGG pathways and GO terms.

From: Widespread evidence of viral miRNAs targeting host pathways

KEGG Pathway

Mouse/Human

Synthesis and degradation of ketone bodies

2/1

C21-steroid hormone metabolism

1/2

ErbB signaling pathway

2/4

Axon guidance

2/3

Olfactory transduction

2/2

Cancer

2/5

GO term

Mouse/Human

Multicellular organismal development

3/5

Neuron development

3/4

Regulation of immune response

4/3

Peptidyl-tyrosine phosphorylation

3/3

Cellular response to retinoic acid

3/3

Integrin binding

3/2

Intermediate filament

3/2

Phosphorylation

3/2

Positive regulation of muscle cell differentiation

3/2

Negative regulation of insulin receptor signaling pathway

5/4

Positive regulation of phosphatidylinositol 3-kinsase activity

3/4

Insulin receptor signaling pathway

3/4

  1. Mouse and human viruses target genes sharing similar cellular signaling pathways and GO terms despite large divergence in 3'UTRs. KEGG pathways and GO terms which were enriched for multiple miRNA and multiple virus strains in one species are listed.