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Table 2 Comparison of prediction result with M1311

From: iStable: off-the-shelf predictor integration for predicting protein stability changes

Predictors

Sn

Sp

Acc

MCC

iStable

0.944

0.981

0.969

0.930

I-Mutant_PDB

0.555

0.922

0.800

0.530

I-Mutant_SEQ

0.702

0.973

0.883

0.734

AUTO-MUTE_RF

0.893

0.991

0.958

0.906

AUTO-MUTE_SVM

0.772

0.975

0.907

0.789

MUPRO_SVM

0.775

0.956

0.896

0.761

PoPMuSiC2.0

0.313

0.941

0.724

0.341

CUPSAT

0.579

0.823

0.742

0.411

Majority Voting

0.737

0.984

0.902

0.779

  1. I-Mutant_PDB: I-Mutant2.0 prediction strategy using PDB ID.
  2. I-Mutant_SEQ: I-Mutant2.0 prediction strategy using protein sequence.
  3. AUTO-MUTE_RF: AUTO-MUTE Random Forest prediction model.
  4. AUTO-MUTE_SVM: AUTO-MUTE SVM prediction model.
  5. MUPRO_ SVM: MUPRO SVM prediction model.
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BMC Bioinformatics

ISSN: 1471-2105

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