Table 1 Variables used in the statistical analysis of geometrically related amino acid pairs (GAAP).

$N_{GAAP}^{+}$

The number of times a geometrically related residues pair occurs in the known CE epitope dataset.

$N_{GAAP}^{-}$

The number of times a geometrically related amino acid pair occurs in the non-CE epitope dataset.

$f_{GAAP}^{+}$

The frequency (%) that a geometrically related amino acid pair occurs in the known CE epitope dataset.

$f_{GAAP}^{-}$

The frequency (%) that a geometrically related amino acid pair occurs in the non-CE epitope dataset.

$Tota{l}_{GAAP}^{+}$

The total number of times that all geometrical amino acid pairs occur in the known CE epitope dataset.

$Tota{l}_{GAAP}^{-}$

The total number of times that all geometrical amino acid pairs occur in the non-CE epitope dataset.

$\mathsf{\text{CE}}{\mathsf{\text{I}}}_{GAAP}$

CEI for a geometrically related amino acid pair.