Figure 5

An example of a volume indicator. (A) A virtual sphere of 10 Å located at the center of anchor residue was constructed to evaluate the total number of potential volume voxels. (B) Seven extended directional vectors of the candidate volume voxel. (C) If a voxel possesses more than or equal to four extended directional vectors intersecting with the protein, the voxel was defined as one of the volume voxels and represented in orange. Voxels within the virtual sphere but not belonging to the volume content are depicted in blue.