Figure 5

Transcription factor overlap comparison with DREM for the influenza response. The inferred TFs from TIDAL (Figure 3) and DREM (Figure 4) are compared to a set of TFs with implicated immune response roles. This 'known' set consists of the union between two external gene signatures: the general pathogen response signature defined in [1] and the core dendritic cell response signature defined in [38], of which only TF are included. The TF list is derived using a mapping of gene symbols in [43] along with the set of genes linked to human TRANSFAC matrices (see Methods).