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Table 11 Agents' parameters and behaviours for case 3

From: Investigating mathematical models of immuno-interactions with early-stage cancer under an agent-based modelling perspective

Agent

Parameters

Reactive behaviour

Proactive behaviour

Effector Cell

mu 1

Dies

 
 

p 1, g 1, q 1 and q 2

 

Reproduces

 

c

Is recruited

 
 

aa and g2

 

Kills tumour cells

Tumour Cell

a

Dies

 
 

a

 

Proliferates

 

aa and g2

Dies killed by effector cells

 
 

g3 and p2

Has growth stimulated

 
 

p4 and tetha

 

Produces TGF-β

 

c

 

Induces effector recruitment

IL-2

alpha, p 3 and g 4

Is produced

 
 

mu 2

Is lost

 

TGF-β

p 4 and tetha

Is produced

 
 

mu 3

Is lost

 
 

p 2 and g 3

 

Stimulates tumour growth