Figure 2

Theoretical estimations of the expected fractions of type A, type B and mixed GC sections. Fractions of GC sections scored as type A (F _A ), type B (F _B ) or mixed (F _Mix ), were estimated using the new model (Eqns. 5-12) for different values of scoring errors $l_{T_A}$ and $l_{T_B}$. 〈n〉, average number of GC founding B cells; $l_{T_A}$, scoring error for B cells of type B, and $l_{T_B}$, scoring error for B cells of type A. Calculations were performed assuming a GC size of M = 5000 cells, and m = 100 cells in a section. Horizontal lines correspond to the observed fractions in [17].