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Figure 3 | BMC Bioinformatics

Figure 3

From: In silico investigation into dendritic cell regulation of CD8Treg mediated killing of Th1 cells in murine experimental autoimmune encephalomyelitis

Figure 3

Mutually exclusive antigenic presentation by DCs. Median DC populations in a sample of 1,000 simulator runs. The graph shows DC populations for control and mutually exclusive presentation experiments. Inspection of data (not shown) confirmed that mutually exclusive DC simulation experiments resulted in no DCs presenting both MBP and TCR-derived peptides. A-Test scores showed a small effect size difference in TCR-derived expression (score = 0.427) and MBP presentation (score = 0.635), although no real scientific significance, and virtually no effect size difference in total DCs (score = 0.503) or cells presenting no antigen (score = 0.478).

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BMC Bioinformatics

ISSN: 1471-2105

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