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Table 1 Chimera detection performances on positive dataset encompassing 50 synthetic fusion events

From: State of art fusion-finder algorithms are suitable to detect transcription-induced chimeras in normal tissues?

Tool

Sensitivity (%)

False discovery rate

FusionFinder

82 (41/50)

10

FusionMap

80 (40/50)

6

TopHat-fusion

80 (40/50)

73

MapSplice

78 (39/50)

23

deFuse

64 (32/50)

4

FusionHunter

40 (20/50)

4

  1. In parenthesis are given the number of fusions
  2. The sensitivity of each tool is given by the number of chimeras detected by each tool divided for the total number of chimeras in the positive dataset. False discovery rate is given as the total number of chimeras detected that do not match any of the positive 50 chimeras.