Skip to main content
Figure 3 | BMC Bioinformatics

Figure 3

From: Parallel comparison of Illumina RNA-Seq and Affymetrix microarray platforms on transcriptomic profiles generated from 5-aza-deoxy-cytidine treated HT-29 colon cancer cells and simulated datasets

Figure 3

Sensitivity and False Discovery Rate (FDR) curve plots for simulated data using each DEG method. Sensitivity (A.) or FDR (B.) are calculated for 4 RNA-Seq DEG methods (SAMSeq, baySeq, DESeq, and NOISeq) and 3 microarray DEG algorithms (T-test, SAM, eBayes). Method curves are shown in different colors (see figure legends) at each 95% minimum fold change level for pre-determined DEGs. Each fold change on x-axis (in log2 scale) corresponds to the lower 5% fold change of normally distributed DEGs predefined in the simulation process (See Methods).

Back to article page

BMC Bioinformatics

ISSN: 1471-2105

Contact us