Table 2 Phyletic distribution of experimentally confirmed and hypothetical peptidase families in MEROPS clan MA

Total phyla

5

28

49

MA(E)

M1

Aminopeptidase N

3

21

31

M2

Angiotensin-converting enzyme

-

6

11

M3

Thimet oligopeptidase

3

25

28

M4

Thermolysin

1

10

4

M5

Mycolysin

-

2

-

M9

Microbial collagenase

1

6

-

M13

Neprilysin

1

12

23

M26

IgA metalloendopeptidase

1

4

-

M27

Tentoxilysin

-

1

-

M30

Hyicolysin

1

9

-

M32

Carboxypeptidase Taq

5

16

7

M34

Anthrax lethal factor

-

1

-

M36

Fungalysin

-

6

5

M41

FtsH endopeptidase

-

27

36

M47

Metallopeptidase PRSM1

-

-

1

M48

Metallopeptidase STE24

4

25

28

M49

Dipeptidyl-peptidase III

-

6

21

M56

BlaR1 peptidase

-

11

-

M60

Enhancin

-

3

1

M61

Glycyl aminopeptidase

2

10

2

M65

YugP protein (Bacillus)

-

3

-

M69

F19C6.4 protein (Caenorhabditis)

-

-

1

M70

Surface protein (Ehrlichia)

-

1

-

M76

Atp23 peptidase

-

-

21

M78

ImmA peptidase

-

10

-

M85

NleC peptidase

-

1

-

M90

MtfA peptidase

-

9

-

M91

NleD peptidase

-

1

-

M93

BACCAC_01431 protein (Bacteroides)

-

1

-

M95

Proabylysin

1

5

-

MA(M)

M6

Immune inhibitor A

1

12

3

M7

Snapalysin

-

1

-

M8

Leishmanolysin

-

7

20

M10

Matrix metallopeptidases

2

11

14

M11

Autolysin

-

2

2

M12

Astacins/reprolysins

1

8

26

M35

Deuterolysin

-

3

3

M39

YIL108W protein (Saccharomyces)

-

-

1

M43

Cytophagalysin

1

6

14

M54

Archaelysin

4

12

8

M57

PrtB protein (Myxococcus)

-

3

-

M59

Putative zinc metalloprotease (Vibrio)

-

1

-

M62

Membrane metalloprotease (Euryarchaeota)

1

3

-

M64

IgA peptidase (Clostridium)

-

5

1

M66

StcE peptidase

-

3

1

M68

JHP0742 protein (Helicobacter)

1

3

-

M71

PAE0478 protein (Pyrobaculum)

1

-

-

M72

Peptidyl-Asp metallopeptidase

-

7

1

M80

Wss1 peptidase

-

-

12

M83

DR2310 peptidase

-

2

-

M84

mpriBi peptidase

1

1

-

M94

Acel_2062 protein (Acidothermus)

--

9

-