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Figure 3 | BMC Bioinformatics

Figure 3

From: Adaptable probabilistic mapping of short reads using position specific scoring matrices

Figure 3

Sensitivity as a function of PPV for BWA-PSSM, BWA, BWA-MEM and Bowtie2 using single-end ART-simulated data. For short reads of length 36 (a) and 50 (b) BWA-PSSM shows greater sensitivity than the other mappers at similar PPV. For reads of length 76 (c) the performance of BWA-PSSM and BWA-MEM is similar, while for reads of length 100 (d) BWA-MEM has slightly higher sensitivity than BWA-PSSM at similar PPV. The curves for each mapping program were obtained by filtering for varying mapping qualities. The results are based on the simulations shown in Table 1. Bowtie and GEM are excluded as they do not provide MapQ scores.

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