Improved multi-level protein–protein interaction prediction with semantic-based regularization

BMC Bioinformatics

Table 3 Results (AUC)

	Independent	Unidirectional			Bidirectional			Full
Level		P → D	D → R	P → R	P ⇔ D	D ⇔ R	P ⇔ R
Results for Yip *et al.*[21]
Proteins	0.723				0.722		0.725	0.724
Domains	0.531	0.619			0.688	0.695		0.673
Residues	0.563		0.542	0.549		0.576	0.659	0.722
Results for SBR
Proteins	0.808				0.820		0.819	0.820
Domains	0.605	0.814			0.837	0.896		0.937
Residues	0.591		0.664	0.671		0.675	0.673	0.676
Results for SBR- ∃ _n
Proteins	0.808				0.820		0.819	0.821
Domains	0.605	0.814			0.837	0.895		0.956
Residues	0.591		0.745	0.760		0.778	0.772	0.797

Area under the ROC curve values attained by Yip et al.[21] , SBR, and SBR- ∃_n (SBR equipped with the n -existential quantifier).

ISSN: 1471-2105