Improved multi-level protein–protein interaction prediction with semantic-based regularization

BMC Bioinformatics

Table 4 Results ( F ₁ )

	Independent	Unidirectional			Bidirectional			Full
Level		P → D	D → R	P → R	P ⇔ D	D ⇔ R	P ⇔ R
Results for Yip *et al.*[21]
Proteins	0.665				0.665		0.666	0.666
Domains	0.518	0.620			0.662	0.659		0.661
Residues	0.522		0.510	0.514		0.602	0.609	0.613
Results for SBR
Proteins	0.718				0.722		0.722	0.723
Domains	0.568	0.693			0.696	0.731		0.750
Residues	0.579		0.605	0.605		0.605	0.605	0.602
Results for SBR- ∃ _n
Proteins	0.717				0.722		0.722	0.722
Domains	0.568	0.693			0.696	0.729		0.757
Residues	0.579		0.635	0.639		0.641	0.644	0.650

F₁ values attained by Yip et al.[21], SBR, and SBR- ∃_n (SBR equipped with the n -existential quantifier).

ISSN: 1471-2105