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Table 2 Performance of Oli , OliMo , OliMoSS , RNAcontext and RPISeq on the AURA_dataset

From: Protein-specific prediction of mRNA binding using RNA sequences, binding motifs and predicted secondary structures

Name #(RBP+) Oli OliMo OliMoSS RNAcontext RPISeq-SVM RPISeq-RF
AGO1 1824 0.86 0.85 0.84 0.83 0.74 0.62
AGO2 207 0.84 0.83 0.70 0.80 0.7 0.61
AGO4 270 0.87 0.84 0.78 0.82 0.76 0.62
AUF1 1319 0.69 0.69 0.67 0.62 0.57 0.6
CPEB1 182 0.69 0.67 0.59 0.55 0.62 0.53
CPEB4 72 0.52 0.54 0.60 0.50 0.54 0.52
CUGBP1 195 0.78 0.78 0.65 0.72 0.72 0.6
ELAVL1 1262 0.73 0.73 0.69 0.68 0.6 0.61
PUM1 420 0.68 0.68 0.66 0.68 0.67 0.64
PABP 258 0.57 0.58 0.52 0.52 0.52 0.51
QKI 710 0.87 0.86 0.86 0.83 0.78 0.76
TNRC6A 246 0.87 0.83 0.79 0.82 0.67 0.67
TNRC6B 742 0.86 0.86 0.82 0.83 0.70 0.68
TNRC6C 151 0.80 0.80 0.68 0.77 0.70 0.61
U2AF65 228 0.73 0.73 0.67 0.71 0.64 0.64
Mean ±sd   0.75 ±0.11 0.75 ±0.10 0.70 ±0.09 0.71 ±0.11 0.66 ±0.07 0.61 ±0.06
  1. The table lists RBPs, the number of sequences and the AUCs for each method on the AURA_dataset. The AUCs are calculated in 10-fold cross validations and at a sequence identity of 80%. The negatives are provided in all cases by 3K- (see Evaluation Evaluation 1). Data are reported with means ± standard deviation (sd).