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Table 3 Main characteristics of tools used as references in this work

From: The discriminant power of RNA features for pre-miRNA recognition

Tool

Algorithm

# Features

Pre-processing

Train

Source

   

(+)

(−)

(+)

(−)

(+)

(−)

Triplet −SVM

SVM

32

noML

B P>18

163

168

5.0

CDS

    

M F E<−15

    
    

noML

    

MiPred

RF

34

noML

B P>18

163

168

8.2

CDS

    

M F E<−15

    
    

50<l e n<138

    
    

noML

    

MicroPred

SVM

21

RR

l e n<151

Not

Not

12

CDS

    

RR

Given

Given

 

ncRNAs

     

Clearly

Clearly

  

G 2DE

G 2DE

7

RR

B P>18

460

460

12.0

CDS

   

noML

M F E<−25

    
    

noML

    

Mirident

SVM

1300

 

B P>18

484

484

11.0

CDS

   

RR

M F E<−25

    
   

noML

50<l e n<138

    
    

RR

    
    

noML

    

HuntMi

RF

28

ExpVal

E−v a l u e≤102

Not

Not

17.0

CDS

     

Given

Given

 

mRNA

     

Clearly

Clearly

 

ncRNA

  1. BP = Number of base pairs on the stem, MFE = Minimum Free Energy of the secondary structure, noML = no Multiple Loops, RR = Removed Redundancies, E-value ≤ 102 = expected value in BLASTN against mirbase, ExpVal = Only experimentally validated precursors and RF = Random forest.
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