Table 6 Not significant (null edge) in MS and in control groups
From: Investigating perturbed pathway modules from gene expression data via structural equation models
Multiple sclerosis (MS) | Control (C) | |||||
|---|---|---|---|---|---|---|
Paths | Type | Estimate | P-value | Estimate | P-value | MS/C |
23396 ← 382 | Activation | 0.114 | 0.657 | 0.082 | 0.324 | OFF/OFF |
10093 ← 7454 | Activation | 0.419 | 0.199 | 0.065 | 0.726 | OFF/OFF |
5580 ← 8612 | Indirect | 0.326 | 0.388 | 5.119 | 0.144 | OFF/OFF |
5894 ← 5580 | Activation | 0.338 | 0.207 | -0.103 | 0.657 | OFF/OFF |
5894 ← 5581 | Activation | 1.399 | 0.436 | -2.815 | 0.349 | OFF/OFF |
5595 ← 5604 | Phoshorylation | -0.107 | 0.808 | -0.963 | 0.408 | OFF/OFF |
1794 ← 1399 | Binding/association | 0.056 | 0.399 | -0.007 | 0.747 | OFF/OFF |
8936 ← 5880 | Activation | 0.015 | 0.972 | -0.410 | 0.240 | OFF/OFF |
7454 ← 382 | Directed path | 0.057 | 0.753 | -0.076 | 0.696 | OFF/OFF |
5604 ← 5338 | Directed path | -0.024 | 0.810 | -0.170 | 0.454 | OFF/OFF |
5595 ← 5338 | Directed path | 0.124 | 0.404 | 0.590 | 0.065 | OFF/OFF |
5338 ← 382 | Activation | 0.164 | 0.612 | 0.216 | 0.007 | OFF/ON |
5580 ← 8613 | Indirect | 3.021 | 0.133 | -0.819 | 0.019 | OFF/ON |
5604 ← 5894 | Activation | 0.160 | 0.183 | 0.273 | 0.041 | OFF/ON |
5321 ← 5595 | Activation | 0.356 | 0.535 | -0.285 | 0.052 | OFF/ON |
382 ← 5880 | Activation | 0.302 | 0.455 | 1.314 | 0.002 | OFF/ON |
5580 ← 382 | Directed path | -0.073 | 0.688 | 0.156 | 0.005 | OFF/ON |
382 ← 1399 | Directed path | 0.144 | 0.414 | 0.970 | 0.001 | OFF/ON |
7454 ← 5338 | Directed path | 0.111 | 0.358 | 1.070 | 0.002 | OFF/ON |
10093 ← 382 | Directed path | 0.269 | 0.252 | 0.498 | 0.001 | OFF/ON |
7454 ← 5880 | String evidence | 0.109 | 0.621 | 0.864 | 0.077 | OFF/OFF |
5581 ← 5595 | String evidence | 0.001 | 0.978 | 0.049 | 0.001 | OFF/ON |
23396 ← 5880 | Activation | 1.207 | 0.000 | 0.079 | 0.708 | ON/OFF |
5581 ← 8613 | Indirect | 0.953 | 0.000 | 0.002 | 0.921 | ON/OFF |
10093 ← 5880 | Directed path | 1.044 | 0.000 | 0.365 | 0.397 | ON/OFF |
8613 ← 1399 | Directed path | -0.024 | 0.027 | -0.093 | 0.225 | ON/OFF |
8936 ← 1794 | Directed path | 1.819 | 0.008 | -1.627 | 0.608 | ON/OFF |
5580 ← 5338 | String evidence | 0.417 | 0.004 | 0.258 | 0.222 | ON/OFF |