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Figure 3 | BMC Bioinformatics

Figure 3

From: DMRforPairs: identifying Differentially Methylated Regions between unique samples using array based methylation profiles

Figure 3

DMRforPairs output. (A) One row of the HTML table describing one DMR. Thumbnail, genomic annotation and descriptive statistics regarding (the difference between) the samples are presented as well as links to figures/tables illustrating the methylation patterns in the samples in detail. Direct links to the genomic region in two genome browsers are also provided (Ensembl & UCSC). Region IDs are generated on the fly by the regionfinder function and are specific to a dataset and to a set of DMRforPairs parameters. They are therefore not interchangeable between datasets/experiments and serve mainly as identifiers during exploration of the dataset. (B) Methylation level per probe (M and β values) plotted against its genomic position. These plots are generated for all relevant and significant regions. (C) Annotated visualization of DMRs (β values) ±10 kb. Black box indicates the DMR. Transcripts overlapping/near the region are retrieved from Ensembl. These plots are optionally generated for all relevant and significant regions. (D) Additional statistics (STATS link in table) as provided for each region.

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