Table 1 Most commonly used relationships for annotation extension statements and examples of their usage
From: A method for increasing expressivity of Gene Ontology annotations using a compositional approach
Contextual relationships | Example (gene product; primary GO term; annotation extension) |
|---|---|
part_of | C. elegans psf-1; nucleus; part_of(WBbt:0006804 body wall muscle cell) |
occurs_in | Mouse opsin-4; G-protein coupled photoreceptor activity; occurs_in(CL:0000740 retinal ganglion cell) |
happens_during | S. pombe wis4; stress-activated MAPK cascade; happens_during(GO:0071470 cellular response to osmotic stress) |
Molecular relationships | Example (gene product; primary GO term; annotation extension) |
has_regulation_target | Human suppressor of fused homolog SUFU; negative regulation of transcription factor import into nucleus; has_regulation_target(UniProtKB:P08151 zinc finger protein GLI1) |
has_input | S. pombe rlf2; protein localization to nucleus; has_input(PomBase:SPAC26H5.03 pcf2) |
has_direct_input | Human WNK4; chloride channel inhibitor activity; has_direct_input(UniProtKB:Q7LBE3 Solute carrier family 26 member 9) |