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Table 3 Benchmark measures on a dataset extracted from the Rath et al. benchmark web server

From: In silico evaluation of the influence of the translocon on partitioning of membrane segments

 

Sensitivity (%)

Specificity (%)

Correctly predicted sequences (%)

PMIscale

80

90

88

Averaged performance of 52 methods

82.6

70.7

66.2

  1. This benchmark contains 599 sequences – 133 membrane proteins TMH or β-barrel and 466 soluble proteins – including 483 membrane helices; the averaged performance was calculated on the 52 transmembrane helix prediction methods with topography information available on the web server - TMLOOP method is not taken into account.