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Table 1 Percentage of all pairs shared by different methods in the set of top L covariation scores: average of 9 protein families

From: Multidimensional mutual information methods for the analysis of covariation in multiple sequence alignments

  2D_MI 3D_MI 4D_MI PSICOV plmDCA GREMLIN hpPCA
2D_MI 80.0 69.9 42.2 34.4 41.6 24.6
3D_MI 79.1 87.9 46.4 36.9 45.0 27.5
4D_MI 67.7 86.3 46.4 38.4 46.2 28.6
PSICOV 38.3 41.6 42.1 34.4 44.4 26.9
plmDCA 29.0 31.5 32.4 32.6 63.9 51.7
GREMLIN 36.4 40.0 40.2 41.9 61.2 42.1
hpPCA 20.2 22.6 23.8 23.2 46.2 37.6
  1. Values above the diagonal. All protein pairs. Values below the diagonal. Only pairs whose residues are separated by at least 20 intervening positions in sequence space.