Figure 6

Estimated global frequency of inversion HsInv0201 in human populations. Allele frequencies of a polymorphic inversion on chromosome 5, calculated with svgem, are shown as colors on top of the topology of a Neighbor-joining tree of some human populations. The tree was built using the SNP-based, genome-wide, Hudson’s F _ST s among the populations as distances [3]. In each bifurcation, the overall frequency was assiged to both sister clades if there were no significant differences. Significant changes are labeled with asterisks (*, p-value < 0.05; **, p - value < 0.001). The numbers of individuals analysed are shown in parentheses, and population labels are: LWK, Luhya (Kenia); YRI, Yoruba (Nigeria); ASW, African-American (Southwest, US); PUR, Puerto Rican; IBS, Iberian (Spain); TSI, Tuscan (Italy); CEU, Utah residents with Northern and Western European ancestry; FIN, Finnish; GBR, British (England, and Scotland); CLM, Colombian; MXL, Mexican; CHB, Han Chinese (Beijing, China); CHS, Southern Han Chinese; JPT, Japanese.