Skip to main content

Table 2 Label of individual HMMER hits (TP, FN, FP, TN) based on E-values of total score, high-quality score and low-quality score

From: On the necessity of dissecting sequence similarity scores into segment-specific contributions for inferring protein homology, function prediction and annotation

Type E-value
Total score High-quality score Low-quality score
TN > 0.1 > 0.1 > 0.1
> 0.1 > 0.1 ≤ 0.1
TP ≤ 0.1 ≤ 0.1 > 0.1
≤ 0.1 ≤ 0.1 ≤ 0.1
FP ≤ 0.1 > 0.1 ≤ 0.1
FN > 0.1 ≤ 0.1 > 0.1
? > 0.1 ≤ 0.1 ≤ 0.1
  ≤ 0.1 > 0.1 > 0.1
  1. Type (?) occurs when the score threshold causes the total score to become insignificant (despite significant high and low-quality score) or vice versa.