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Table 2 Label of individual HMMER hits (TP, FN, FP, TN) based on E-values of total score, high-quality score and low-quality score

From: On the necessity of dissecting sequence similarity scores into segment-specific contributions for inferring protein homology, function prediction and annotation

Type

E-value

Total score

High-quality score

Low-quality score

TN

> 0.1

> 0.1

> 0.1

> 0.1

> 0.1

≤ 0.1

TP

≤ 0.1

≤ 0.1

> 0.1

≤ 0.1

≤ 0.1

≤ 0.1

FP

≤ 0.1

> 0.1

≤ 0.1

FN

> 0.1

≤ 0.1

> 0.1

?

> 0.1

≤ 0.1

≤ 0.1

 

≤ 0.1

> 0.1

> 0.1

  1. Type (?) occurs when the score threshold causes the total score to become insignificant (despite significant high and low-quality score) or vice versa.