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Figure 1 | BMC Bioinformatics

Figure 1

From: Detecting overlapping protein complexes based on a generative model with functional and topological properties

Figure 1

An example which illustrates the biological motivation. This is an interaction map of SAGA complex, transcription factor TFIID complex (CYC2008 benchmark) and the complexes detected by our model that match with them on Gavin network. Proteins are labeled according to the complex(es) to which they belong: rectangle represents SAGA complex; circle represents transcription factor TFIID complex; diamond represents proteins shared by the two complexes; octagon represents proteins with other functions; and hexagon represents GO terms. Shaded areas represent complexes detected by our model (a) using solely the PPI network and (b) using both the PPI network and the total GO annotation.

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