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Table 2 Functional enrichment of the complexes detected using only the unweighted PPI network

From: Detecting overlapping protein complexes based on a generative model with functional and topological properties

Network

Algorithm

<E(-15)

E(-15) to E(-10)

E(-10) to E(-5)

E(-5) to 1

Collins

GMFTP

33 (18.4%)

24 (13.4%)

60 (33.5%)

62 (34.6%)

 

Linkcomm

53 (13.0%)

59 (14.5%)

109 (26.8%)

186 (45.7%)

 

SR-MCL

38 (11.3%)

36 (10.7%)

92 (27.3%)

171 (50.7%)

Gavin

GMFTP

29 (10.7%)

20 (7.4%)

54 (19.9%)

168 (62.0%)

 

Linkcomm

29 (4.8%)

34 (5.6%)

112 (18.5%)

429 (71.0%)

 

SR-MCL

49 (6.7%)

29 (3.9%)

135 (18.4%)

522 (71.0%)

Krogan core

GMFTP

28 (10.4%)

22 (8.1%)

63 (23.3%)

157 (58.1%)

 

Linkcomm

24 (5.6%)

30 (7.1%)

114 (26.8%)

257 (60.5%)

 

SR-MCL

80 (4.4%)

70 (3.8%)

264 (14.4%)

1419 (77.4%)

Krogan extended

GMFTP

29 (10.9%)

19 (7.2%)

57 (21.5%)

160 (60.4%)

 

Linkcomm

30 (3.0%)

41 (4.1%)

158 (15.8%)

769 (77.1%)

 

SR-MCL

135 (5.1%)

86 (3.3%)

259 (9.8%)

2164 (81.8%)

DIP

GMFTP

36 (9.6%)

29 (7.7%)

68 (18.1%)

242 (64.5%)

 

Linkcomm

44 (2.4%)

63 (3.4%)

323 (17.7%)

1398 (76.5%)

 

SR-MCL

174 (5.4%)

117 (3.6%)

398 (12.3%)

2533 (78.6%)

BioGRID

GMFTP

66 (15.2%)

38 (8.8%)

113 (26.0%)

217 (50.0%)

 

Linkcomm

217 (4.9%)

254 (5.7%)

1026 (23.1%)

2949 (66.3%)

 

SR-MCL

166 (15.1%)

77 (7.0%)

210 (19.2%)

643 (58.7%)