Evaluation of GSA-MPSAs of P450 clusters viewed from various aspects. (A) Total number of outlier indels. (B) Difference in the total numbers of concordant and discordant introns. (C) The sum of standard deviations of sequence lengths in variable regions. The total computational time spent for iterative refinement with 10 CPUs is also indicated. (D) The total sum of normalized weighted sum-of-pairs scores of all GSA-MPSAs. The results obtained from the original annotation are indicated by blank bars. Of the 21 combinations of template modes, the best combination for each aspect is indicated by the thick bar.