Phenotype prediction based on genome-wide DNA methylation data

BMC Bioinformatics

Table 5 Numbers of genes overlapping to 1,591 developmental genes

	Normal	Normal HPV+	Normal HPV-	CIN2+(a)	CIN2+(b)	Cancer
t	126	112	77	217	93	138
	151	137	81	232	82	163
	61	62	84	75	100	46
MWU	113	110	71	200	93	126
	127	126	91	218	76	166
	59	66	72	84	122	47
Bartlett	142	156	160	194	185	222
	195	198	161	243	206	240
	96	89	113	84	100	45
Levene	127	139	79	224	133	264
	157	159	96	244	175	271
	71	74	83	80	80	40
Age-corr.	161	188	129	108	102	109
Age-corr.	206	219	171	118	126	98
	71	86	62	81	59	95

Genes corresponding to the 1000 most significant CpGs taken (five tests: t-test, Mann–Whitney U test, Bartlett’s test, Levene’s test and test for methylation-age-correlation, mean length of gene lists: 931). The three rows per cell correspond to all, hyper- and hypo-CpGs. Significant overlaps (p < 0.01) are shown in bold.

ISSN: 1471-2105