Figure 6From: KVFinder: steered identification of protein cavities as a PyMOL pluginSpace segmentation of ALDH1 channel. A) Analysis of the substrate access channel ALDH1 [PDB:1BXS]. The catalytic cysteine (Cys 302) is highlighted in stick representation. B) Space segmentation of the substrate access channel, substrate binding site is represented in blue and the NAD binding site in cyan. Volume determination of this second subpocket is essential, as its size is directly correlated with the protein functionality [35].Back to article page