Detecting protein complexes in protein interaction networks using a ranking algorithm with a refined merging procedure

Table 2 Testing ProRank + on small complexes

Dataset	Predicted complexes	Matched complexes	Sn	Acc	MMR
Collins	428	91	0.875	0.935	0.433
Krogan core	229	34	0.667	0.816	0.163
Krogan extended	260	78	0.75	0.769	0.217
Gavin	534	57	0.897	0.947	0.293
BioGRID	823	78	0.882	0.9	0.351

The results are in terms of (a) the number of clusters that match the reference complexes, (b) the geometric accuracy (Acc) which reflects the clustering-wise sensitivity (S_n) and the clustering-wise positive predictive value (PPV), and (c) the maximum matching ratio (MMR).

ISSN: 1471-2105