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Table 2 BRAF clusters

From: A spatial simulation approach to account for protein structure when identifying non-random somatic mutations

Hotspot

Center

Within sphere

# Mutations

A

465

(464, 465, 466)

8

B

470

(469, 470, 471)

7

C

596

(595, 596, 597)

7

  1. The three hot spots identified by SpacePAC for the BRAF structure (PDB ID: 3Q96) at an optimal radius of 4Å. See Figure 7 for a visual orientation.
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BMC Bioinformatics

ISSN: 1471-2105

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