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Table 4 ALK clusters

From: A spatial simulation approach to account for protein structure when identifying non-random somatic mutations

Hotspot

Center

Within sphere

# Mutations

A

1174

(1173, 1174, 1175)

11

B

1275

(1274, 1275, 1276)

12

  1. The two hot spots identified by SpacePAC as significant for the ALK Structure (PDB ID: 2XBA) [44] at an optimal radius of 4Å. See Figure 8 for a visual orientation.
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BMC Bioinformatics

ISSN: 1471-2105

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