Skip to main content
Figure 5 | BMC Bioinformatics

Figure 5

From: Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models

Figure 5

Differential network backbone values of TNF-IL1 α -TLR-NF κ B network for the comparison IFX responders vs. IFX non-responders from the two cohorts GSE12251 & 14580, showing stronger network perturbation for the IFX non-responder group. Blue shading indicates a negative value while red shading a positive one. The leading nodes are circled with green. Grey edges represent an activation while black edges an inhibition. Almost four thousands genes are underlying this network (Table 3).

Back to article page

BMC Bioinformatics

ISSN: 1471-2105

Contact us