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Table 2 Overview of the datasets used

From: Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models

Data ID

Tissue

Treatment

GSE7895

Bronchial Brushing

Smokers (30), non-smokers (20), former smokers (51)

GSE19667

Bronchial Brushing

Smokers (65), non-smokers (45)

GSE12251 & GSE1480

Colonic biopsies

Responders (20) and non-responders (27) pre-treatment

GSE16879

Colonic biopsies

Responders (8) and non-responders (16) pre-/post-treatment

E-MTAB-1842, GSE50254

Rat parenchyma

Main stream smoke (8, 15, or 23 μg nicotine/l) or fresh air. 5 animals per group.

E-MTAB-1272

NHBE cells

2, 4, 6 and 8 hours after washing of CDK4/6 inhibitor. 3 samples per group.

E-MTAB-1311

NRBE cells

Vehicle control or TNF α (0.1, 1, 10, 100 ng/ml) × (30 min, 2 h, 24 h). 3 samples per group

  1. GSE identifiers refer to datasets in Gene Expression Omnibus (GEO, http://www.ncbi.nlm.nih.gov/geo/) and E-MTAB identifiers to dataset deposited in ArrayExpress (http://www.ebi.ac.uk/arrayexpress/). The number of samples per group is indicated in parenthesis.