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Table 2 Overview of the datasets used

From: Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models

Data ID Tissue Treatment
GSE7895 Bronchial Brushing Smokers (30), non-smokers (20), former smokers (51)
GSE19667 Bronchial Brushing Smokers (65), non-smokers (45)
GSE12251 & GSE1480 Colonic biopsies Responders (20) and non-responders (27) pre-treatment
GSE16879 Colonic biopsies Responders (8) and non-responders (16) pre-/post-treatment
E-MTAB-1842, GSE50254 Rat parenchyma Main stream smoke (8, 15, or 23 μg nicotine/l) or fresh air. 5 animals per group.
E-MTAB-1272 NHBE cells 2, 4, 6 and 8 hours after washing of CDK4/6 inhibitor. 3 samples per group.
E-MTAB-1311 NRBE cells Vehicle control or TNF α (0.1, 1, 10, 100 ng/ml) × (30 min, 2 h, 24 h). 3 samples per group
  1. GSE identifiers refer to datasets in Gene Expression Omnibus (GEO, and E-MTAB identifiers to dataset deposited in ArrayExpress ( The number of samples per group is indicated in parenthesis.