Category | Gene-level | Enrichment | 28-day rat inhalation | 28-day rat inhalation | RLAK study | RLAK study | CDKi study | Complete match with |
---|---|---|---|---|---|---|---|---|
statistics | statistics | TNF-IL1-NFKB | xenobiotic | TNF-IL1-NFKB | Xenobiotic | cell cycle | biological expectations | |
Forward FCS | t | mean | ×/ √ | ×/ √ | √/(√) | ./ × | ×/ √ | 0 |
maxmean | ×/ × | (√)/ √ | ×/ × | ./ × | ×/ √ | 0 | ||
GSEA | ×/ × | ×/ √ | ×/(√) | ./(√) | ×/ √ | 0 | ||
fc | mean | (√)/ √ | (√)/ √ | (√)/ √ | ./ × | ×/ √ | 0 | |
maxmean | √ / √ | √ / √ | (√)/(√) | ./ × | ×/ √ | 2 | ||
GSEA | ×/ √ | ×/ √ | ×/(√) | ./ × | ×/ √ | 0 | ||
Backward ORA | fdr | RCR | ×/ × | √/ × | ×/ × | ./ √ | √/ × | 1 |
Backward FCS | t | mean | ×/ × | ×/ √ | ×/ × | ./ √ | √/(√) | 1 |
maxmean | ×/ × | ×/(√) | ×/ × | ./ √ | √/ × | 1 | ||
t | GSEA | ×/ × | ×/ √ | ×/ × | ./ √ | √/ × | 1 | |
fc | mean | (√)/(√) | √/(√) | √/(√) | ./ √ | √/(√) | 1 | |
maxmean | √ / √ | √/ × | √ / √ | ./ √ | √/(√) | 3 | ||
GSEA | ×/ √ | ×/ √ | ×/ × | ./ √ | √/ × | 1 | ||
NPA | (√)/ √ | na | √ / √ | na | na | 1 | ||
Backward PT | fc | TopoNPA | √ / √ | √ / √ | √ / √ | ./ √ | √ / √ | 5 |