Figure 1
From: A method to incorporate prior information into score test for genetic association studies
The difference in theoretical power (vertical axis) of the proposed test and the score test as a function of the total non-centrality parameter r (horizontal axis) at the type-1 error rate α = 0.05. Each curve corresponds to the number of SNPs in the single causal group L1 given in the legend (Panels 1 and 2), the number of groups K (Panel 3), and the number of causal groups m (Panel 4). The parameters for each of the Panels are as follows: Panel 1: L = 10, K = 2; Panel 2: L = 100, K = 10; Panel 3: L = 50, L1 = 5; Panel 4: L = 54, K = 6, equal number of SNPs in each group, and equal non-centrality parameters in all causal groups.