Causative gene rank cumulative distribution function. The cumulative distribution function of causative gene rank for the four simulated scenarios taken across the 33 simulated diseases. The solid lines are the results obtained when ranked by similarity score. The dashed lines are the results obtained when ranked by p-value. The x-axis is the rank, r, and the y-axis is the probability that the causative gene rank, R, is less than or equal to r. Note that the x-axis is on a logarithmic scale.