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Table 3 The statistical significance (p-values) of SP and TC score differences between HMMsato and the other two tools on the test data set

From: Enhancing HMM-based protein profile-profile alignment with structural features and evolutionary coupling information

Tools

p-value of SP scores

p-value of TC scores

HMMsato -- HHsearch (without secondary structure information)

1.078 X 10−6

3.414 X 10−7

HMMsato -- HHsearch (with secondary structure information)

0.7538

0.8082

HMMsato -- HHsuite (without secondary structure information)

1.724 X 10−8

1.515 X 10−9

HMMsato -- HHsuite (with secondary structure information)

0.1535

0.1087