Figure 1

Overview of ELM server and web interface. Users input NGS data as a zip file (~1 Gb). (1) The web server matches NGS reads against known viral genomes using BLAST [12]. (2) Taxonomic classification based on the LCA is performed using MEGAN under the top 10% score filter [8]. (3) In ELM analyisis, multiple comparisons of the LCA assignments are performed under different top percent score filters. The server displays the results with the ratings of taxa.