Inference of perturbed oncogenic miRNA regulatory network in colorectal cancer. (A) ROC curves of predicting CRC related miRNAs (families) using different methods. (B) The perturbed key miRNA regulatory sub-network in CRC. Genes are colored on the basis of their expression fold change. (C) Enrichment results of the 538 LE target genes in KEGG pathways. The number of LE genes included in each pathway is shown beside the bar.