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Table 3 Enrichment results of validated and also CRC related miR-145 targets in the LE target sets

From: Inferring the perturbed microRNA regulatory networks from gene expression data using a network propagation based method

Validated 6 12 12 25
Other 43 216 282 655
Total 49 228 297 680
  ap-value = 0.014 ap-value = 0.194 ap-value = 0.204  
  1. aP-value result of Fisher’s exact test using a contingency table integrating the data of the current and the 4th columns, it indicates the statistical significance of the current LE target set enriching with larger proportion of validated and functional miR-145 targets than the background target set.