Inferring the perturbed microRNA regulatory networks from gene expression data using a network propagation based method

Table 3 Enrichment results of validated and also CRC related miR-145 targets in the LE target sets

	NP-method.LE	GSEA.LE	GR.GSEA.LE	miR-145.target
Validated	6	12	12	25
Other	43	216	282	655
Total	49	228	297	680
	^ap-value = 0.014	^ap-value = 0.194	^ap-value = 0.204

^aP-value result of Fisher’s exact test using a contingency table integrating the data of the current and the 4th columns, it indicates the statistical significance of the current LE target set enriching with larger proportion of validated and functional miR-145 targets than the background target set.

ISSN: 1471-2105