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Table 1 Type I errors of the multiple version of LCT and NLCT GSA methods, with dimension of the multiple phenotypes set at q= 10

From: Gene set enrichment analysis for multiple continuous phenotypes

Method

ρ

n = 20

n = 50

  

p = 20

p = 50

p = 100

p = 20

p = 50

p = 100

LCT

0.0

0.050

0.047

0.047

0.052

0.043

0.047

 

0.3

0.051

0.053

0.050

0.055

0.045

0.043

 

0.6

0.050

0.054

0.042

0.051

0.042

0.048

 

0.9

0.053

0.052

0.044

0.058

0.050

0.046

NLCT

0.0

0.041

0.039

0.035

0.062

0.049

0.058

 

0.3

0.042

0.047

0.051

0.061

0.052

0.043

 

0.6

0.044

0.062

0.047

0.052

0.049

0.042

 

0.9

0.050

0.060

0.049

0.044

0.053

0.051