Figure 4
From: A phenome-guided drug repositioning through a latent variable model
Relations between variables in LDA model. (A) Latent variables (topics) are used to construct paths from drugs to phenotypes. P(t|d) is the probability that drug d is associated with topic t while P(ph|t) defines the probability of phenotype ph associated with topic t. (B) Graphical representation of LDA for phenome. In this framework, M stands for the number of drugs, and N is the number of phenotypes.