Skip to main content

Table 1 Indications retrieved by the model

From: A phenome-guided drug repositioning through a latent variable model

Findings supported by drug labels

Drug

Indication

Rank

Reference

Thioridazine

Schizophrenia

1

DB00679

Mesoridazine

Schizophrenia

1

DB00933

Bromazepam

Insomnia

4

DB01558

Nitrazepam

Insomnia

3

DB01595

Pipotiazine

Schizophrenia

1

DB01621

Nilotinib

Leukemia

6

DB04868

Findings supported by literature

Drug

Indication

Rank

Reference

Apomorphine

Anxiety

6

[25]

Metyrapone

Cancer

6

[26]

Prilocaine

Analgesia

3

[27]

Sevoflurane

Sedation

1

[28]

Remifentanil

Sedation

1

[29]

Methohexital

Muscle relaxation

2

[30]

Isoflurane

Sedation

3

[31]

Disulfiram

Ulcer

1

[32]