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Table 2 Statistics for cell-type trees on H3K4me3 data

From: Study of cell differentiation by phylogenetic analysis using histone modification data

 

hESC

Epithelial

Fibroblast

Blood

Astrocytes

Myocytes

Endothelial

Skeletal muscle

SR

PD

 

(5)

(8)

(16)

(2)

(2)

(1)

(2)

(1)

 

(%)

WM (one replicate)-ENCODE

5,0

6,1

8,4

2,0

1,1

1,0

1,1

1,0

0.93

3.20

OM (one replicate)-ENCODE

5,0

4,1

6,3

2,0

2,0

1,0

1,1

1,0

0.92

3.94

OM (one replicate)-ENCODE-MP

5,0

4,2

6,4

2,0

1,1

1,0

1,1

1,0

0.63

-

WM (one replicate)-MACS2

5,0

4,2

14,1

2,0

2,0

1,0

1,1

1,0

0.88

5.51

OM (one replicate)-MACS2

5,0

4,2

13,3

2,0

2,0

1,0

1,1

1,0

0.89

4.84

WM (all replicates)-ENCODE

5,0

6,1

11,2

2,0

1,1

1,0

1,1

1,0

0.84

3.30

OM (all replicates)-ENCODE

5,0

4,2

9,4

2,0

2,0

1,0

1,1

1,0

0.78

3.88

WM (all replicates)-MACS2

5,0

4,2

14,1

2,0

2,0

1,0

1,1

1,0

0.63

5.31

OM (all replicates)-MACS2

5,0

4,2

15,1

2,0

2,0

1,0

1,1

1,0

0.65

5.18

WM (all replicates)-TP-ENCODE

5,0

6,1

7,4

2,0

1,1

1,0

1,1

1,0

0.81

3.73

OM (all replicates)-TP-ENCODE

5,0

4,3

8,5

2,0

2,0

1,0

1,1

1,0

0.74

3.98

OM (profile)-ENCODE

5,0

4,3

12,2

2,0

2,0

1,0

1,1

1,0

0.90

4.05

  1. 2nd to 9th columns show the number of cells (of the same type) belonging to the largest and second-largest clades; the total number of cells of that type is in the top row. Rows correspond to various methods (WM: windowing; OM: overlap; TP: top peaks with threshold of 10). The second last column shows the SR ratio. The last column contains the percent deviation (PD) of the distances between the leaves found using the NJ tree from the Hamming distance between the leaves. ENCODE means peaks from ENCODE data is used while MACS2 means peaks from MACS2 program is used. (one replicate) means only one replicate for each cell type is used, (all replicates) means all available replicates (1, 2, or 3) for each cell type is used, (profile) means a profile representation created using all replicates for each cell type is used. MP - maximum parsimony using TNT software.