Table 1 Transformed genotype dataset for the 18 mutation sites and the 58 samples
From: Using single cell sequencing data to model the evolutionary history of a tumor
Gene (site) ∖ | |||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sample ID | 1 | 2 | 3 | 5 | 6 | 7 | 8 | 9 | 12 | 16 | 18 | 19 | 20 | 22 | 24 | 25 | 26 | 29 | 30 | 31 | 36 | 37 | 40 | 41 | 43 | 44 | 45 | 47 | 48 |
PDE4DIP (A →G) | - | - | - | 1 | 1 | 0 | - | 0 | - | - | - | 0 | - | - | - | - | - | - | 1 | - | - | - | 0 | - | 0 | - | 1 | 0 | - |
NTRK1 (A →G) | - | 0 | - | - | 1 | - | - | - | - | 2 | - | 2 | 1 | 1 | - | - | 1 | - | 2 | - | - | 1 | - | - | 0 | 0 | - | - | 2 |
SESN2 (C →T) | 1 | 1 | 1 | - | - | - | - | 1 | 1 | 1 | 2 | - | - | 1 | - | - | - | 0 | 0 | 1 | - | 2 | 2 | - | 0 | 2 | 0 | 1 | 1 |
ARHGAP5 (G →A) | - | 1 | - | - | - | 0 | 0 | 2 | - | - | - | - | 0 | 1 | 1 | - | - | - | - | 0 | - | 1 | - | - | 0 | - | 0 | 0 | - |
DNAJC17 (C →G) | 1 | - | 1 | - | - | - | - | 0 | - | 1 | 0 | - | - | - | - | - | - | 2 | 1 | - | - | - | - | - | 1 | 2 | - | 2 | 1 |
USP32 (C →T) | - | - | - | 1 | 0 | - | - | 1 | - | - | - | - | 0 | 0 | 0 | - | - | - | 0 | - | - | - | - | - | - | 1 | 0 | 1 | 0 |
ANAPC1 (G →A) | - | - | - | 1 | 0 | 1 | 0 | 1 | - | 1 | 0 | - | 1 | 1 | 0 | 1 | 1 | 0 | 2 | - | 0 | - | - | 0 | 0 | 0 | 0 | 1 | - |
RETSAT (C →T) | - | 0 | - | 1 | 0 | 0 | - | - | - | 0 | - | - | - | 0 | - | 0 | 0 | - | 0 | - | 0 | - | 0 | - | 0 | - | 0 | 0 | - |
ST13 (G →A) | 0 | 0 | - | - | - | - | 0 | 1 | 1 | 1 | - | 0 | 1 | - | - | 1 | - | - | 1 | 0 | 1 | 1 | - | 0 | 0 | 1 | - | 1 | - |
DLEC1 (T →C) | - | - | - | - | - | - | - | 1 | - | 1 | - | - | 0 | 2 | 2 | 2 | - | - | 1 | - | - | 1 | - | - | - | - | 2 | 1 | 1 |
FRG1 (G →A) | 0 | 0 | 1 | 0 | 0 | - | 0 | - | 0 | 0 | 0 | 0 | - | - | - | 0 | - | - | 0 | - | - | - | 0 | 0 | 0 | - | 0 | 1 | 0 |
DMXL1 (G →A) | 2 | - | - | 1 | - | 0 | - | 1 | - | 2 | - | - | - | 2 | - | 0 | 0 | 1 | 1 | - | 2 | - | 1 | - | 0 | - | - | - | - |
FAM115C (T →C) | - | - | - | - | 0 | - | - | - | - | - | - | 0 | - | - | - | - | 0 | - | - | - | - | - | - | - | - | 2 | 0 | 0 | - |
MLL3 (C →T) | - | - | 0 | - | 0 | 0 | - | 0 | 0 | 0 | 1 | - | 0 | - | 0 | - | 0 | 0 | 1 | 0 | 1 | 1 | 0 | - | 0 | 0 | 0 | - | - |
ABCB5 (G →T) | 1 | - | - | 1 | - | - | 1 | 2 | 1 | 0 | 1 | - | - | 0 | 0 | - | - | 2 | 2 | - | - | 2 | - | - | - | - | 1 | - | - |
ASNS (T →A) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | - | 0 | 0 | 0 | - | 0 | 0 | 1 | 1 | 0 | - | 0 | 1 | 1 | 1 | - | 0 | 1 | 0 | - | 0 |
PABPC1 (C →T) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - | 1 | - | 0 | - | - | 0 | 0 | 0 | - | - | 0 | 0 | - | 0 | 0 | - | 1 | 0 | - | 0 | 0 |
TOP1MT (A →G) | - | - | - | - | - | - | - | - | - | - | - | 0 | - | - | - | - | - | - | - | 0 | 2 | 2 | 1 | - | - | 1 | - | 1 | - |
Gene (site) ∖ | |||||||||||||||||||||||||||||
Sample ID | 49 | 50 | 52 | 54 | 56 | 60 | 61 | 63 | 66 | 69 | 70 | 72 | 73 | 74 | 76 | 78 | 79 | 80 | 82 | 86 | 87 | 88 | 89 | 90 | 91 | 93 | 94 | 97 | 100 |
PDE4DIP (A →G) | - | - | - | - | 1 | - | 0 | - | - | - | 0 | - | 0 | 1 | 0 | 0 | - | 0 | 0 | 1 | - | 0 | - | - | - | - | 1 | 1 | - |
NTRK1 (A →G) | - | 2 | 1 | 0 | - | - | 1 | - | - | 0 | 1 | 1 | - | 0 | 0 | 1 | 1 | 0 | 1 | - | 0 | - | - | 0 | - | 0 | 0 | 1 | 2 |
SESN2 (C →T) | 1 | 0 | 0 | 0 | 1 | - | 1 | 0 | 1 | - | - | 1 | 0 | 1 | 2 | 2 | - | 1 | 1 | 1 | 2 | 1 | 0 | 0 | 1 | 2 | 2 | 1 | 1 |
ARHGAP5 (G →A) | 1 | 0 | - | - | 0 | 0 | - | - | 0 | - | 1 | 0 | 0 | 0 | - | 0 | 0 | 1 | 1 | - | 0 | 0 | - | - | 0 | 1 | 0 | 1 | 0 |
DNAJC17 (C →G) | 1 | - | 1 | 0 | 1 | 1 | - | 1 | 1 | 1 | 1 | 2 | - | 1 | 0 | 1 | 0 | 1 | 1 | - | 1 | - | 0 | - | - | 1 | - | 2 | 1 |
USP32 (C →T) | 0 | 0 | 1 | 0 | 1 | 0 | 0 | - | 1 | 0 | 0 | - | - | - | - | - | 0 | - | 0 | 1 | - | 0 | 1 | 1 | - | 0 | 0 | 0 | - |
ANAPC1 (G →A) | 0 | 0 | 1 | - | 0 | - | - | 0 | 0 | 1 | - | 0 | - | 0 | 0 | - | - | - | 1 | 0 | - | 0 | 0 | - | - | - | 0 | - | 0 |
RETSAT (C →T) | 1 | 0 | 1 | 0 | - | 0 | 1 | 0 | 0 | 1 | 0 | 0 | - | 0 | 1 | 1 | - | 1 | 0 | 0 | - | 0 | 0 | - | 1 | 1 | 0 | 0 | - |
ST13 (G →A) | - | 0 | 1 | - | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | - | 0 | - | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | - | 1 | 0 |
DLEC1 (T →C) | - | - | - | 2 | - | 2 | - | - | 1 | - | - | - | - | 2 | 2 | 0 | 1 | - | - | - | - | - | - | - | 0 | 2 | - | - | 1 |
FRG1 (G →A) | 0 | 0 | 0 | - | 0 | 0 | 1 | 1 | 0 | - | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | - | 1 | 0 | - | 0 | 0 | 0 | 0 |
DMXL1 (G →A) | 1 | - | 1 | - | 1 | 1 | 0 | 0 | 1 | - | 1 | - | - | - | - | 2 | - | - | - | 0 | - | - | 0 | - | 1 | - | 0 | 2 | - |
FAM115C (T →C) | - | - | - | - | 1 | - | - | - | - | - | - | - | - | 0 | - | 1 | - | - | - | - | 0 | - | 1 | - | - | - | - | - | - |
MLL3 (C →T) | 0 | 1 | 1 | 1 | - | 1 | 0 | - | 0 | - | 0 | - | 0 | 0 | - | - | 0 | 0 | 0 | 0 | 0 | - | 0 | 0 | - | 1 | - | - | 0 |
ABCB5 (G →T) | - | - | - | - | 1 | 1 | 1 | - | 1 | 0 | 0 | - | - | 1 | 0 | - | 1 | 0 | - | 1 | - | - | 1 | - | - | - | - | 0 | - |
ASNS (T →A) | - | 1 | - | 0 | - | 1 | - | - | 0 | - | 0 | 0 | - | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - | - | 1 | 0 |
PABPC1 (C →T) | 0 | 0 | 0 | 0 | - | 0 | - | 0 | 0 | 0 | 0 | - | - | 0 | - | 0 | - | 0 | 1 | 0 | 0 | - | 0 | - | 0 | 1 | - | 0 | 0 |
TOP1MT (A →G) | 1 | 2 | - | 2 | 2 | 0 | - | - | - | - | 1 | - | 1 | - | 1 | - | - | 1 | 2 | - | - | - | - | 2 | 1 | - | 0 | - | 1 |