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Table 2 Comparing the enhancer with the threshold classifier of approximately equal specificity on synthetic scores assigned to surface residues of protein complexes taken from the data set PlaneDimers and the KL-subset

From: CRF-based models of protein surfaces improve protein-protein interaction site predictions

Data Set Score Precisionς Classifier Specificity Sensitivity MCC
  0.8 Threshold Predictor 0.9672 0.2562 0.3253
  Enhancer 0.9666 0.4281 0.4911
PlaneDimer 0.9 Threshold Predictor 0.9618 0.2556 0.3077
  Enhancer 0.9624 0.4086 0.4610
  1.0 Threshold Predictor 0.9611 0.2428 0.2912
  Enhancer 0.9612 0.3872 0.4379
  1.1 Threshold Predictor 0.9681 0.2100 0.2753
  Enhancer 0.9677 0.3307 0.4045
  1.2 Threshold Predictor 0.9649 0.2100 0.2648
  Enhancer 0.9647 0.3213 0.3854
  0.8 Threshold Predictor 0.9568 0.2936 0.3549
  Enhancer 0.9577 0.3586 0.4210
KL-subset 0.9 Threshold Predictor 0.9533 0.2843 0.3369
  Enhancer 0.9531 0.3290 0.3820
  1.0 Threshold Predictor 0.9570 0.2559 0.3152
  Enhancer 0.9571 0.2971 0.3591
  1.1 Threshold Predictor 0.9615 0.2279 0.2949
  Enhancer 0.9614 0.2743 0.3459
  1.2 Threshold Predictor 0.9604 0.2199 0.2828
  Enhancer 0.9599 0.2516 0.3175