Known and novel SNVs classification based on comparison with dbSNP. A) The proportion of the novel/known SNVs in breast cancer cases and control. The last bar indicates SNVs that overlap in case and control. B) Distribution of common and rare SNVs in dbSNP. As expected SNVs that are rare (found in less than 10% of the samples analyzed) have a lower chance of being found in dbSNP. C) Functional annotation of novel and known SNVs. For functional groups that have lower numbers a zoomed-in view is shown.