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Figure 2 | BMC Bioinformatics

Figure 2

From: BESST - Efficient scaffolding of large fragmented assemblies

Figure 2

Dispersity score. Illustration of dispersity measurement. Read pairs linking contigs c1 and c2 of lengths n and m respectively are transformed to data tested with the KS-test. (a) Observations from contig c1 are translated and reflected on the x-axis while observations from contig c2 are translated. The two sample KS statistic will indicate high similarity in read distribution. (b) Strange placement of linked reads occur. Several explanations are possible. One possible explanation is that contig c2 is misassembled (chimeric) and another explanation is that c2 is a correctly assembled contig with small repeated regions solved on assembly level. The repeat might not be present in other contigs from the assembly and therefore, the alignments to these regions are reported as unique. Contig c2 is however not close to the to contig c1 on the genome and linked reads fail to place at the non-repeated regions on c2. The KS test will indicate low similarity

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